The Montreal Protocol on Substances That Deplete the Ozone Layer is an international treaty designed to protect the ozone layer by phasing out the production of numerous substances that are responsible for ozone depletion. It was agreed on 16 September 1987, and entered into force on 1 January 1989. Since then, it has undergone several amendments and adjustments, with revisions agreed to in 1990 (London), 1992 (Copenhagen), 1995 (Vienna), 1997 (Montreal), 1999 (Beijing), 2007 (Montreal), 2016 (Kigali) and 2018 (Quito).[2][3][4] As a result of the international agreement, the ozone hole in Antarctica is slowly recovering.[5] Climate projections indicate that the ozone layer will return to 1980 levels between 2040 (across much of the world) and 2066 (over Antarctica).[6][7][8] Due to its widespread adoption and implementation, it has been hailed as an example of successful international co-operation. Former UN Secretary-General Kofi Annan stated that "perhaps the single most successful international agreement to date has been the Montreal Protocol".[9][10] In comparison, effective burden-sharing and solution proposals mitigating regional conflicts of interest have been among the success factors for the ozone depletion challenge, where global regulation based on the Kyoto Protocol has failed to do so.[11] In this case of the ozone depletion challenge, there was global regulation already being installed before a scientific consensus was established. Also, overall public opinion was convinced of possible imminent risks.[12][13]